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B 12 deficiency can also result in neurological problems
N = 2 biological replicates for c , d , (representative data) and N = 1 for h , and i
Serum is the most common sample type, though it yields concentrations approximately tenfold higher than plasma because BDNF stored in platelets is released during the clotting process
assuming patients continued oral semaglutide and liraglutide treatment alongside basal insulin before discontinuing and intensifying to basal-bolus insulin therapy when an HbA1c threshold of 8.0% (64 mmol/mol) was exceeded for a second time (with an associated HbA1c reduction applied from the insulin-experienced multivariate equations published by Willis et al.)
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