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The largest study so far found no increase in stone risk versus metformin

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10.1345/aph.1D007 19 BuonfiglioF.Wasielica-PoslednikJ.PfeifferN.GerickeA

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No strong baseline therapy modifier seen.[11][1] Strategies to Mitigate Regain Gradual tapering may ease rebound, though unproven in large RCTs

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