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Animals (Basel)
doi: 10.1016/j.jplph.2014.12.014 4 ChenI
Proteinogenic amino acid proline protects cell from environmental stress factors by several protective mechanisms such as osmoprotectant, acting as chemical chaperone by stabilization of proteins and antioxidant enzymes, chelation of metals, scavenging ROS, balancing the intracellular redox homeostasis (NADP + /NADPH ratio, GSH pool) and participating in cellular metabolic signaling
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