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It has been proven safe and effective and has been shown to be relatively well tolerated among test patients according to a study published in the US National Library of Medicine/National Institutes of Health
The development of novel therapeutic targets, including the IRG1/itaconate pathway or selective activation of pentose phosphate pathway branches, also warrants further investigation
Trends Genet 2000
They can be found in the cytoplasm, nucleus and mitochondria (Kupis et al., 2016)
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