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"Metastatic melanomas of unknown primary show better prognosis than those of known primary: a systematic review and meta-analysis of observational studies"
This is the same physiologic process seen when someone stops lifting weights: muscle size decreases because the stimulus is gonenot because muscle is being destroyed. Common Misconception: GLP-1 Drugs Burn Muscle Reality: Muscle loss during GLP-1associated weight loss is driven by reduced mechanical load and insufficient protein/calories , not by a toxic or catabolic drug effect. When Lean-Mass Loss Becomes True Muscle Wasting True muscle wasting is uncommon with GLP-1 therapy and is usually related to undernutrition , not the medication itself
Wu G, Haynes TE, Li H, Yan W, Meininger CJ
Sin embargo, revisiones ms amplias concluyen que el efecto es trivial: no se puede afirmar que sea bueno ni malo
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