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Ishida, J., Saitoh, M., Ebner, N., Springer, J., Anker, S
Among them, CDCA was identified as the most effective FXR ligand, while DCA and LCA were the preferred agonists of Takeda G protein-coupled receptor 5 (TGR5) (70)
That SFN injected directly into Arabidopsis leaves has been reported to lead to a rapid decrease of the cellular glutathione pool 75 further strengthens the involvement of glutathione in ITC-triggered growth inhibition
While effective, this approach carries risks including supraphysiological hormone levels, suppression of natural GH production, and side effects such as fluid retention, joint pain, carpal tunnel syndrome, and potential insulin resistance
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