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Given the FoxO1 ablation induced -cell dedifferentiation and caused hyperglycemia under physiologic stress 22 , we determined whether LOsG/ROS stresses decrease FoxO1 expression and thus induce -cell dedifferentiation
A recent study compared the functionality of mitochondrial transfer with or without Pep-1 conjugation in 6-OHDA-induced PC12 cells and PD rat models (Chang et al., 2016)
D- as well as L-methionine were found to be equally effective, suggesting that depletion of sulfur was at the root of the primary defect and that it was unrelated to protein synthesis
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