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Additionally, mitochondrial fission increased in the kidneys of DKD mice, suggesting that HQDSD can prevent kidney damage caused by T2DM by inhibiting Pink1/Parkin-mediated mitophagy, thereby exerting a protective effect on the kidneys
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When added to foods, it helps maintain their freshness and quality
Consequently, a significant proportion of administered nanocarriers is prematurely sequestered and cleared by the reticuloendothelial system (RES)particularly the liver and spleensubstantially limiting the effective dose that reaches the osteosarcoma TME (69, 70)
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