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Mittal G, Mason LJ, Isenberg DAJFR (2007) Immunopathogenesis of systemic lupus erythematosus
In rats subjected to experimental hypoxia, a significant stress-mediated reduction in both the rate of phosphorylated respiration (V3, a 20% decrease) and the rate of ADP phosphorylation (ADP/t, a 31% decrease) was observed in brain mitochondria
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It means youre essentially self-experimenting with a compound that has strong theoretical mechanisms, solid animal data, massive anecdotal support, and minimal human clinical validation
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