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But what's happening on a practical level when you take it
These kinases phosphorylate the membrane transporters (DAT, NET, SERT), leading to two outcomes: the transporters are either internalized into the cell (ceasing all reuptake function) or they undergo a conformational shift that causes them to operate in reverse
Molineros, J
To avoid a fragmented focus on weight or pregnancy rates alone, clinical intuition can be formalized into an Expected Net Utility framework: Where P represents the probability of key outcomes and w represents the patients preference weights for those outcomes
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