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PMID: 19238460 Prescription Information: rxlist.com (cocaine / topical) rxlist.com (Goprelto ) topical cocaine nasal spray Keywords Imipramine Trade Name: Tofranil Drug Class: TCA antidepressant (tricyclic amine) Mechanism of Action: Blocks presynaptic reuptake transporters for norepinephrine & serotonin (NET & SERT) on nerve endings (therapeutic effects) Antimuscarinic (contributes to side effects) Antihistamine (contributes to side effects) Alpha receptor blocking properties (contributes to side effects) Several weeks to months are required for antidepressant effects to appear (or be significantly greater than a placebo), although its direct effects (e.g

Gauge (G) refers to needle diameterhigher numbers indicate thinner needles

If you are sensitive to or allergic to benzyl alcohol, you should also avoid it (a preservative in some GSH products)

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