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According to the recently completed ELIXA and LEADER trials, an increase in HR, regardless of its magnitude, does not appear to increase the cardiovascular risk of individuals with T2DM and with (or at high risk of) cardiovascular disease
Despite this potential, given the known long-term benefit of lowering hemoglobin A1c in preventing DR progression, there does not appear to be any contraindication to initiating GLP-1/GIP agonist therapy with appropriate ocular monitoring
Theres a big difference between bleaching and brightening
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