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The most frequently reported adverse effects of Rybelsus are gastrointestinal in nature , occurring particularly during the initial weeks of treatment as the body adjusts to the medication
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For users on tirzepatide monotherapy, blood sugar related sleep disruption is usually mild and resolves as the body adapts to the new metabolic patterns, typically within 2-4 weeks of starting or increasing the dose
5,6 Pharmacists should be well versed in EDKA and its precipitating factors in order to educate patients and clinicians on the signs and management of EDKA in patients taking SGLT2i
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