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Also known as Ibutamoren, its an orally administered compound without major side effects

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Retatrutide also improved insulin sensitivity and glucose metabolism beyond what youd expect from weight loss alone, suggesting direct receptor-mediated effects on metabolic tissues

However, they also emphasize the importance of considering the lipid composition of these diets, as well as encouraging caution around their use in the absence of strategies to block metabolic compensation (such as Cpt1a inhibition), which can enable the use of lipids as metabolic fuels to promote tumor growth 76,77,78