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In breast cancer cells, a high level of miR-378* induces the metabolic shift from an oxidative to a glycolytic bioenergetics pathway by inhibiting the expression of two PGC-1 partners, ERR (estrogen-related receptor gamma) and GABPA (GA binding protein transcription factor, alpha subunit)
Experts believe that combining these two peptides may lead to a synergistic effect that stems from their unique mechanisms of action
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Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation
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