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A collaborative discussion between patient and provider can determine the most appropriate course of action, which may include further diagnostic evaluation, treatment of underlying contributing factors, symptomatic management of RLS, or consideration of alternative diabetes or weight management therapies if symptoms are severe and refractory to other interventions
When asked about potential mechanisms by which semaglutide itself and not just the weight loss it causes could do harm, Drucker said, Its possible [it] does have effects on, for example, placental blood flow or formation of the placenta
Lilly is studying retatrutide in several phase 3 clinical trials to evaluate its potential efficacy and safety across several indications, including obesity and overweight with 1 weight-related medical problem, type 2 diabetes, knee osteoarthritis, moderate-to-severe obstructive sleep apnea, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease
"The more sick you feel, the less you're going to eat," Yeo says
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