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Of note, NAC not only prevents death of non-tumor lymphoid cells in gels but also enables their growth under these conditions

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To improve the selectivity, in this work, we design and synthesize a malononitrile-functionalized TPE derivative, TPE-DCV, which can undergo addition reaction with thiol group to the alkene bond, leading to the change in its fluorescence in the system (Figure 1)

The melanoma study discussed below provides the strongest evidence for this selective activity