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This gradual dosage is intended to reduce gastrointestinal adverse drug responses

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If the ultrasound indicates a full stomach or produces inconclusive results, surgeons should consider delaying the procedure or managing the patient as a full stomach. Although specific guidance on the precise timing of reinitiating GLP-1 RAs postoperatively is not explicitly outlined, it may be reasonable to hold these medications in the immediate postoperative period and resume with a similar approach as other diabetes medications that pose a low risk of hypoglycemia

Semaglutide has a half-life of approximately one week, tirzepatide about 5 days, and liraglutide approximately 13 hours, meaning the medication clears from your system within several weeks of your last injection