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Phase 2 trials used a structured titration protocol, typically starting at 0.5 mg once weekly and escalating to maintenance doses of up to 12 mg once weekly
This study suggests that bariatric surgery does not sufficiently reduce obstructive sleep apnea and warrants mandatory postoperative sleep test in order to precisely re-evaluate at least all severe OSA patients regardless of the postoperative weight loss or patient-reported resolution of symptoms
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Gastrointestinal effects during transitions Nausea is the most common side effect of both medications, affecting roughly 44% of semaglutide users and a similar percentage of tirzepatide users in clinical trials
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