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Proliferation (log 2 doublings, 5 days) of indicated GPX4-deficient cell lines in vitro either untreated or supplemented with cholesterol (5 g/mL), combined native LDL and HDL (50 g/mL), combined tristearin-reconstituted LDL and HDL (rLDL+rHDL, 50 g/mL), or Fer-1 (1 M)
10.1034/j.1399-3054.1999.106103.x 120 Pavan KumarB
92 However, none of these CLRs are entirely specific to a single-cell type, and both their expression patterns and the genes themselves can vary across species
Caution should be exercised in treating HIV-positive patients with lipodystrophy with tesamorelin if they develop glucose intolerance or diabetes, and careful consideration should be given to discontinuing tesamorelin treatment in patients who do not show a clear efficacy response as judged by the degree of reduction in visceral adipose tissue by waist circumference or CT scan measurements
