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All patients should be catheterised to prevent strictures in the urethra, which also allows accurate monitoring of fluid balance

Beyond the issue of overdiagnosis in prodromal or ambiguous cases, polypharmacy remains prevalent even among correctly diagnosed patients

Other likely effects of high iodine intake in susceptible individuals are an increased production of thyroid-infiltrating T helper 17 cells, inhibition of T regulatory cell development and an abnormal expression of TNF-related apoptosis-inducing ligand in thyrocytes, resulting in apoptosis and tissue destruction ( Reference Duntas 28 )