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GLP-1 RAs mimic the bodys natural GLP-1 gut hormone, which people who have obesity or Type 2 diabetes may secrete less of
However, the large molecular weight, strong hydrophilicity and easy enzymatic hydrolysis of AOD 9604 result in its low bioavailability and limit its clinical application.The rise of nanotechnology has brought revolutionary changes to drug delivery systems
These companies currently offer five GLP-1 drugs approved for type 2 diabetes, with four also approved for various cardiovascular conditions
Tepper SJ, Johnstone MR
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