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Foresta, P

The relative quantification of metabolites was determined by the peak area of the precursor ion, which was normalized to total protein

These shifts in metabolism are often global across the brain, e.g., in a meta-analysis, the conditions of eyes closed versus open, sevoflurane and desflurane anesthesia, and comas of varying levels all demonstrated a global shift, whereas only congenitally blind versus sighted demonstrated localized changes [61]