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Additionally, recent research shows that cystathionine -lyase (CSE) drives astrocytes toward a neurotoxic phenotype in PD by forming a complex with Yes-associated protein (YAP), which activates Forkhead box D3(FOXD3)-mediated transcription of neuroinflammation-related genes (Zhu et al., 2024)

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Through this multidimensional synthesis, we aim to provide a therapeutic strategy more closely aligned with the complexities of real-world decision-making in gynecological and reproductive medicine