In placebo-controlled trials of semaglutide injection for type 2 diabetes mellitus, fatigue, dysgeusia, and dizziness were reported in greater than 0.4% of semaglutide-treated patients
DSS-induced colitis in mice elicited pronounced symptoms, including reduced locomotor activity, decreased consumption of food and water, dull and lifeless fur, signs of depression-like behavior, huddling behavior, perianal swelling and congestion, diarrhea, bloody stools, and substantial weight loss
Patients in the hypertonic saline group experienced more effective diuresis, shorter hospital stays, and a reduced rate of re-admission: LaFreniere G 2017: Effects of hypertonic saline solution on body weight and serum creatinine in patient with acute decompensated heart failure This is a prospective cohort study describing 47 patients with refractory acute decompensated heart failure treated with hyperdiuresis at Quebec University Hospital Centre
Individuals taking medication should discuss potential interactions with their healthcare professional