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Laboratory studies of murine and non-human primates have demonstrated increased liver fat, hepatic inflammation, oxidative stress, and mitochondrial dysfunction in offspring of obese mothers fed a high-fat diet,(Reviewed in 9,33 ) The results of our metabolomic analysis of cord plasma add to the existing literature and suggest that lipotoxicity and increased oxidative stress also occur in infants born to mothers with obesity

The enzymes returned to baseline after medication discontinuation, confirming the elevations were reversible and non-pathological in the vast majority of cases

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In this review, we summarize and discuss the relationship between carnitine and NAFLD, effects of L-carnitine (the biologically active form of carnitine) supplementation in NAFLD, and related diseases, including non-alcoholic steatohepatitis (NASH), cirrhosis, hepatic cellular cancer (HCC), alcoholic fatty liver disease, and viral hepatitis