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Educational campaigns increasingly include webinars, clinical newsletters, continuing medical education resources, and point-of-care messaging

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It differs from the native 70 residue growth factor by an arginine-for-glutamate substitution at position 3 and a hydrophobic 13 residue N-terminal extension, MFPAMPLLSLFVN, which is itself a residual fragment of the methionyl porcine growth hormone fusion partner used to express the protein in Escherichia coli

This helps offset the list price but does not always translate into lower costs for patients, especially those in high-deductible plans