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HA-344 and #231 as dual inhibitors of GPX4 and TXNRD1 in AML cells In the same line, we recently designed two covalent small molecule inhibitors, that can concomitantly inhibit GPX4 and TXDNR1, two critical proteins involved in the protection of cell from ferroptosis and apoptosis [39]

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These drugs are effective for weight loss because they increase insulin levels, which turns the body into a "fat-burning machine," in addition to suppressing appetite