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For this purpose, we treated normal aging mice with intraperitoneal injection of FOXO4-DRI at a dose of 5 mg/kg for 1 month
These cofactors work synergistically when injected with Vitamin B12
The synergy becomes clear: AOD-9604 mobilises fat, but that mobilisation is wasted if mitochondria lack the NAD+ cofactors required to oxidise fatty acids through beta-oxidation and the Krebs cycle
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