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However, the landscape is still evolving

In Canada, Wegovy is indicated as an adjunct to a reduced calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m 2 or greater (obesity), or 27 kg/m 2 or greater (overweight) in the presence of at least one weight-related comorbidity such as hypertension, type 2 diabetes mellitus, dyslipidemia, or obstructive sleep apnea

Its also important to understand that semaglutide does not eliminate hunger completely, as that would be obvious

Addressing the "great unknowns" of HS require a deeper investigation into the functional duality of MMPs and TIMPs