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When theres sub-optimal glucose and highly active neurons have limited access to energy, they dysfunction and ultimately die on a chronic basis. The most active neurons are in regions of learning and memory, Fillit said, making them more susceptible to glucose deprivation and, ultimately, neurodegeneration

[13] [15] Additionally, GLP-1 medications slow gastric emptying, prolonging the time food remains in the stomach and contributing to increased satiety

By opening a lower-cost entry point, Novo Nordisk is building a pipeline of future insured patients while preventing drop-offs during early dose escalation historically a vulnerable period when costs and side effects collide

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