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Clinical experience underscores the potential and subtlety of its impact
Compared to classical gastroprotective peptides such as sucralfate or proton pump inhibitors (PPIs), it acts via a completely different pathway: restoration of mucosal microcirculation rather than acid reduction or formation of a mechanical protective layer
Together, these actions accelerate wound healing, improve tissue strength and elasticity, and support homeostatic recovery following injury or inflammation 1,5
Nausea: the most common side effect Nausea affected approximately 27% of retatrutide users in clinical trials across all doses
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