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HIV protease inhibitorsritonavir, indinavir, saquinavir, nelfinavir, and zidovudinewere described as ABCC1 substrate [35], suggesting that the overexpression of ABCC1 in infected cells makes these cells more resistant to chemotherapy
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Preliminary expert recommendations published in 2001 were subsequently formalized into comprehensive guidelines in 2002, which continue to provide pivotal scientific direction (519, 520)
The protective association was strongest among women with low alcohol intake and faded toward no effect at around 16 grams per day (roughly one beer or glass of wine)
