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Semaglutide studies show that lean mass loss typically accounts for 26% to 40% of total weight lost
However, the weight loss observed in the SELECT study (9.4%) was lower than that seen in previous STEP studies.23 The study design, which was not focused on obesity, may have influenced the lower-than-expected weight reduction, which did not parallel the trend in MACE reduction
Responses were transformed to a linear scale of 0 (worst) to 100 (best) QOL-scores
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