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Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs
Published research has confirmed this hypothesis specifically for hair follicle biology: AHK-Cu has the most direct published evidence for hair follicle effects, while GHK-Cu has the broader regenerative biology across multiple tissue types
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