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Thus, the aim of this study was to determine whether pancreas-derived or intestine-derived GLP-1 is the predominant source of the plasma GLP-1 that increases with DPP-4 inhibitors and that, in combination with an increase in GIP, drives the improvements in glucose regulation
Significant weight loss typically occurs over several months, depending on adherence to the treatment plan
Lancet 2, 13001304, doi: S0140-6736(87)91194-9 (1987)
doi: 10.1002/oby.22726 24 le RouxCWAstrupAFujiokaKGreenwayFLauDCWVan GaalLet al
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