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Here we determine that FUS/TLS directly binds the SMN protein, with its association mediated by the RGG motifs in FUS/TLS and the Tudor domain in SMN
Our results showed that the contribution of the TSS pathway on de novo cysteine synthesis and GSH generation is only detectable under cystine-restricted conditions, and such function is dimmed when cystine is supplemented at supraphysiological concentrations
This drug passes into breast milk
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