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Furthermore, survodutide at doses of 1.8 mg or higher resulted in more substantial weight loss than semaglutide 1.0 mg after the same treatment period

This activates matrix metalloproteinase-9, a proteolytic enzyme involved in tissue remodeling and inflammation via extracellular matrix degradation (Barron et al., 2024)

The treated mice also had a higher ratio of glutathione to glutathione disulfide, the molecule that glutathione becomes after it neutralizes free radicals