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Nat Rev Rheumatol 21 , 671683 (2025)
doi:10.1111/j.1478-3231.2010.02264.x 171
Patients who may not be candidates include those with: Certain endocrine conditions that affect hormone regulation A personal or family history of specific thyroid disorders Pregnancy or breastfeeding Other medical contraindications identified during clinical evaluation In these situations, physicians may recommend different strategies focused on lifestyle, nutrition, or non-injectable therapies
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