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Gazz Med Ital Arch Sci Med 179:479485 Tudosa R, Vartej P, Horhoianu I, Ghica C, Mateescu S, Dumitrache I (2010) Maternal and fetal complications of the hypothyroidism-related pregnancy
The loop of Henle is permeable to urea due the presence of the UT-A2 transporter in the thin descending limb such that when the glomerular filtrate reaches the distal convoluted tubule (DCT) the concentration of urea can be on the order of 7 times that of the plasma
Hormone-Related Side Effects Sprintec's higher estrogen dose (35 mcg) compared to Junel Fe (30 mcg) may increase the risk of estrogen-related side effects such as headaches or blood clots, especially in smokers over 35 or those with certain medical conditions
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