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A big part of how GLP-1s work is reducing the signals your body uses to tell you that you're hungry
Periodic Assessment Taking breaks between cycles provides opportunity for assessment
This dual mechanism of pharmacokinetic buildup plus physiological adaptation explains why many patients report progressive appetite reduction over their first 8 to 12 weeks
Bulk-forming laxatives such as ispaghula husk (Fybogel) or sterculia (Normacol) work by absorbing water in the intestine, increasing stool bulk and stimulating natural peristalsis
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