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12 This pattern is driven by physiological factors like metabolic adaptation and plateauing weight loss, as well as behavioral challenges such as medication fatigue and the persistent nature of obesity

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Phase 2b completed in T2D) Status: Investigational not approved by FDA or EMA Heres what makes it different from everything else on the market and in the pipeline: - Semaglutide (Ozempic/Wegovy/Rybelsus): GLP-1 only - Tirzepatide (Mounjaro/Zepbound): GLP-1 + GIP - Retatrutide (investigational): GLP-1 + GIP + Glucagon - Amycretin : GLP-1 + Amylin Different receptor pairing