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SBP reduction was mostly mediated by weight loss (7794%) in SURPASS-1, -2 and -3, while mechanisms independent from weight loss accounted for most of the tirzepatide benefit on SBP in SURPASS-4 and -5 (57 and 73%, respectively) [77]
Understanding proper administration technique helps ensure you receive the full benefit of your treatment
The phase 2 type 2 diabetes trial evaluated maintenance doses including 0.5 mg, 4 mg, 8 mg, and 12 mg, with several escalation designs [5]
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