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Despite a negative trial of oral Ozempic in mild Alzheimers, the rationale for GLP-1 drugs in neurodegenerative disease remains strong
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Furthermore, there may be concerns regarding the long-term safety profile and uncommon adverse effects associated with GLP-1 receptor agonists, which may limit their use in specific patient populations
Drugs targeting weight management accounted for nearly half of the increase in drug spend in 2024, and the average list price for a GLP-1 is around $1,000 per month
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