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Pediatrics 1994;93:893-5
(2022) demonstrated that hydrophilic BAs, particularly ursodeoxycholic acid (UDCA) and its conjugates, can alleviate oxidative damage through multiple coordinated mechanisms, including direct scavenging of reactive oxygen species, activation of Nrf2-dependent endogenous antioxidant defenses, stabilization of mitochondrial function, and suppression of oxidative stress-associated inflammatory and apoptotic signaling
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