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Re-analysis of completers: A re-analysis of the same study data that excluded participants who discontinued treatment showed somewhat more encouraging results: 87.5% of those who received alpha-lipoic acid (versus 59.1% of placebo recipients) experienced a modest reduction in hepatic steatosis, and this difference was statistically significant

Based on the current status of the Phase 3 TRIUMPH program, Eli Lilly is expected to file a New Drug Application (NDA) in late 2026

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Adaptive and intermittent therapies Another strategy involves targeting specific resistance mechanisms to resensitize tumors before rechallenging them with previously ineffective drugs