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Because semaglutide is a potent medication, dosing errors, whether intentional or accidental, can lead to unintended exposure to higher amounts than planned and increase the risk of side effects
Simulated gastric fluid was produced by dissolving 200 mg sodium chloride and 64 mg pepsin from porcine stomach mucosa (Sigma-Aldrich) in 100 mL distilled water, adding 0.7 mL hydrochloric acid and adjusting the pH to 1.2
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