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Vitamin C is a water-soluble vitamin that plays a crucial role in immune function, collagen synthesis, and antioxidant defense, and may also support cardiovascular health and cognitive function

These barriers are physically represented by the so-called tight junctions between brain endothelial cells and epithelial cells, attributed to the special proteins such as occludin, claudins, and the associated proteins zona occludens (ZO-1, ZO-2, and ZO-3), which are highly expressed in brain endothelium (Chen et al., 2009

All referenced findings derive from published preclinical and clinical research, and results in one model may not translate to another.