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The phase 2 and phase 3 trials focused primarily on total body weight reduction
[0059] When condensing the second AEEA, use a reaction system in which the molar ratio of 2-chlorotriphenyl chloride resin / Fmoc-AEEA-OH / HATU / DIPEA is 1:2:2:2.4, and react for 1.5h to obtain Fmoc-AEEA-AEEA- Resin, use 20% piperidine / DMF to deprotect after synthesis, the deprotection time is: 5+15min
Treating the disorder, also known as AUD or alcoholism, can be difficult to manage and no new medications have been approved for AUD in nearly two decades
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