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Kruse, along with chemist Jesper Lau and technician Paw Bloch, set out to create a version of GLP-1 , a natural hormone that helps the body produce insulin and regulate appetite
Preclinical studies have evaluated KD primarily in SOD1 transgenic mouse models, which exhibit progressive motor neuron degeneration, muscle weakness, and mitochondrial dysfunction, thereby recapitulating key features of disease progression [40, 102]
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10.1016/j.neulet.2016.11.064 56
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